Win10 sync mail application error 0x80c8043e how to do

Method one, solve through Powershell
After entering Powershell in the Cortana search bar, right click on the first result and select “Run as administrator”, then enter the following Enter after the command:
Get-appxprovisionedpackage –online |  Where-object {$_.packagename –like “*windowscommunicationsapps*”} |  Remove-appxprovisionedpackage –online

After the run, re-download and install the Mail & Calendar app in the store. Of course, if this method doesn't work, you can try the following “civil program”.
Method 2, uninstall KB3081436 update
This patch is the second cumulative update received by the official version of Win10, used to fix various problems in the system. However, the patch itself has caused a lot of trouble for some users, such as the inability to install, or the "extra-segmentation" after installation, the 0x80c8043e error mentioned in this article is one of them.
It should be noted that this security update can be uninstalled without uninstalling. Although you may have installed the third cumulative update patch KB3081438 recently released, there are still some risks in uninstalling the patch. In particular, if your third update installation fails, it's best to try not to solve the synchronization problem of Mail and Calendar in this way.

Uninstallation method is very simple, click Settings & Rarr; Update & Security & Rarr; Advanced Options & Rarr; View Update History & Rarr; Uninstall Update, then find KB3081436 in the pop-up window, double-click to uninstall.